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WHO, UNAIDS and UNICEF modify recommendations for cotrimoxazole prophylaxis in children:
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1,2,3,4,5,6,7,8,9,10,11
What doses of cotrimoxazole should be used?
- Syrup use is recommended in very young children up to 10-12 kg
- Recommended dosages of 6-8 mg/kg once daily should be used.
- Once tablets can be taken, half of a standard adult tablet crushed may be used for children up to 10kg, one whole tablet for 10-25kg, two single strength or one double strength for over 25kg (a usual single strength tablet provides Sulfamethoxazole 400 mg and trimethoprim 80 mg).
- Use weight band dosages rather than body surface area doses
- If the child is allergic to cotrimoxazole, dapsone is the best alternative
WHO, UNAIDS and UNICEF modify recommendations for cotrimoxazole prophylaxis in children:
1,2,3,4,5,6,7,8,9,10,11
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