Bulletin of the World Health Organization

Two-year impact of single praziquantel treatment on infection in the national control programme on schistosomiasis in Burkina Faso

Seydou Touré, Yaobi Zhang, Elisa Bosqué-Oliva, Césaire Ky, Amado Ouedraogo, Artemis Koukounari, Albis F Gabrielli, Bertrand Sellin, Joanne P Webster, Alan Fenwick

Volume 86, Number 10, October 2008, 780-787

Table 1. Schistosoma haematobium prevalence and intensity of infection in the longitudinal cohort children before and after treatmenta

Variable Baseline(95% CI) 1 year post-treatment(95% CI) 2 years post-treatment(95% CI) Overall reduction in %
Prevalence in %
Overall prevalence (n=763) 59.6 (56.2–63.1) 6.2 (4.5–7.9) 7.7 (5.8–9.6) 87.1
By region
Boucle du Mouhoun (n=238) 48.3 (42.0–54.7) 8.4 (4.9–11.9) 12.2 (8.0–16.3) 74.7
Nord (n=259) 53.7 (47.6–59.7) 0.8 (0.0–1.8) 2.3 (0.5–4.1) 95.7
Sahel (n=199) 89.4 (85.2–93.7) 12.1 (7.5–16.6) 11.6 (7.1–16.0) 87.0
Sud Ouest (n=67) 34.3 (23.0–45.7) 1.5 (0.0–4.4) 1.5 (0.0–4.4) 95.6
By sex
Boys (n=403) 64.3 (59.6–68.9) 7.7 (5.1–10.3) 11.4 (8.3–14.5)b 82.3
Girls (n=360) 54.4 (49.3–59.6) 4.4 (2.3–6.6) 3.6 (1.7–5.6) 93.4

Intensity of infection in e/10 ml
Overall mean (n=763) 94.2 (76.4–111.9) 1.0 (0.2–1.9) 6.8 (1.6–12.0)b 92.8
By region
Boucle du Mouhoun (n=238) 76.4 (52.9–100.0) 0.7 (0.2–1.3) 19.2 (2.7–35.6)b 74.9
Nord (n=259) 63.4 (38.7–88.2) 0.0 (0.0–0.1) 0.8 (0.0–1.7) 98.7
Sahel (n=199) 167.7 (117.9–217.4) 3.0 (0.0–6.1) 2.0 (0.5–3.5) 98.8
Sud Ouest (n=67) 57.7 (11.5–103.9) 0.1 (0.0–0.1) 0.1 (0.0–0.3) 99.8
By sex
Boys (n=403) 115.9 (91.0–140.8) 1.6 (0.1–3.20) 12.1 (2.4–21.8)b 89.6
Girls (n=360) 69.9 (44.7–95.1) 0.3 (0.1–0.6) 0.8 (0.0–1.7) 98.9

CI, confidence interval; e/10 ml, number of eggs per 10 ml urine.a All data at 1 or 2 years post-treatment were significantly lower than at baseline (all P < 0.01).b P < 0.05, significantly higher when compared with 1 year post-treatment.

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