Bulletin of the World Health Organization

Two-year impact of single praziquantel treatment on infection in the national control programme on schistosomiasis in Burkina Faso

Seydou Touré, Yaobi Zhang, Elisa Bosqué-Oliva, Césaire Ky, Amado Ouedraogo, Artemis Koukounari, Albis F Gabrielli, Bertrand Sellin, Joanne P Webster, Alan Fenwick

Volume 86, Number 10, October 2008, 780-787

Table 3. Cross-sectional analysis of Schistosoma haematobium infection in the 7-year-old first-year schoolchildren before and after treatmenta

Variable Baseline(95% CI) 1 year post-treatment(95% CI) 2 years post-treatment(95% CI) Overall reduction in %
Prevalence in %
Overall prevalence 41.6 (33.8–49.3) 7.1 (4.3–10.1) 14.2 (10.4–18.0) 65.9
(n = 154) (n = 307) (n = 317)b
By region
Boucle du Mouhoun 35.6 (23.4–47.8) 0 (N/A) 6.7 (0.4–13.0) 81.2
(n = 59) (n = 20) (n = 60)
Nord 51.4 (35.3–67.5) 4.0 (0.2–7.9) 2.0 (0.0–4.8) 96.1
(n = 37) (n = 99) (n = 98)
Sahel 92.0 (81.4–100.0) 16.7 (9.6–23.7) 30.0 (21.8–38.2) 67.4
(n = 25) (n = 108) (n = 120)b
Sud Ouest 0 (N/A) 0 (N/A) 7.7 (0.0–16.1)
(n = 33) (n = 80) (n = 39)
By sex
Boys 39.8 (29.2–50.3) 6.0 (2.2–9.8) 18.4 (12.5–24.4) 53.8
(n = 83) (n = 150) (n = 163)b
Girls 43.7 (32.1–55.2) 8.3 (4.0–12.6) 9.7 (5.1–14.4) 77.8
(n = 71) (n = 157) (n = 154)

Intensity of infection in e/10 ml
Overall mean 63.5 (30.0–97.0) 4.9 (0.0–11.4) 13.7 (2.5–24.8) 78.4
(n = 154) (n = 307) (n = 317)b
By region
Boucle du Mouhoun 63.7 (22.2–105.3) 0 (N/A) 33.6 (0.0–80.3) 47.3
(n = 59) (n = 20) (n = 60)
Nord 44.0 (0.0–100.5) 1.1 (0.0–2.7) 0.1 (0.0–0.2) 99.8
(n = 37) (n = 99) (n = 98)
Sahel 175.6 (10.9–340.2) 13.0 (0.0–31.5) 14.5 (0.0–31.3) 91.7
(n = 25) (n = 108) (n = 120)b
Sud Ouest 0 (N/A) 0 (N/A) 14.5 (0.0–38.5)
(n = 33) (n = 80) (n = 39)
By sex
Boys 91.2 (33.4–148.9) 1.0 (0.0–2.1) 24.9 (3.3–46.6) 72.7
(n = 83) (n = 150) (n = 163)b
Girls 31.2 (4.1–58.2) 8.7 (0.0–21.4) 1.7 (0.5–3.0) 94.6
(n = 71) (n = 157) (n = 154)

CI, confidence interval; e/10 ml, number of eggs per 10 ml urine; N/A, not available; n, sample size in the group.a Except in Sud Ouest, all data at 1 year or 2 years post-treatment were significantly lower than at baseline (all P < 0.01).b P < 0.05, significantly higher when compared with 1 year post-treatment.

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