Bulletin of the World Health Organization

Global epidemiology of haemoglobin disorders and derived service indicators

Bernadette Modell, Matthew Darlison

Volume 86, Number 6, June 2008, 480-487

Table 3. Estimated reach of treatment for β thalassaemia in each WHO regiona

WHO region Estimated annualbirths β thalassaemias
Transfusion
No. of known patients Adequate iron chelation
Inadequate or no iron chelation
Total Transfusion-dependent Annual no. starting transfusion % of transfusion-dependent patients transfused Annualdeaths because not transfused % with chelation No. with chelation No. of patients Annual deaths due to iron overload
African 1 386 1 278 35 2.7 1 243
American 341 255 134 52.4 121 2 750 58 1 604 1 146 57
Eastern Mediterranean 9 914 9 053 1 610 17.8 7 443 39 700 27 10 818 28 882 1 444
European 1 019 920 140 15.5 780 16 230 91 14 754 1 476 74
South-east Asian 20 420 9 983 962 9.6 9 021 35 500 19 6 621 28 879 1 444
WesternPacific 7 538 4 022 108 2.7 3 914 3 450 44 1 504 1 946 97
World 40 618 25 511 2 989 11.7 22 522 97 630 39 37 866 59 764 2 988

a All figures are minimum estimates.

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