Bulletin of the World Health Organization

Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries

Martin WG Brinkhof, François Dabis, Landon Myer, David R Bangsberg, Andrew Boulle, Denis Nash, Mauro Schechter, Christian Laurent, Olivia Keiser, Margaret May, Eduardo Sprinz, Matthias Egger, Xavier Anglaret, for the ART-LINC of IeDEA collaboration

Volume 86, Number 7, July 2008, 559-567

Table 4. Programme factors associated with the three study outcomes in the first 6 months after starting ART

Programme factors No follow-up
Initially followed-up, then lost
Death
Odds ratioa(95% CI) P-valueb Hazard ratioa(95% CI) P-valueb Hazard ratioa(95% CI) P-valueb
Treatment access 0.055 0.46 0.031
Free of charge 1 1 1
Fee for service 3.71 (0.97–16.05) 1.69 (0.42–6.77) 4.64 (1.11–19.41)
Follow-up 0.58 0.21 0.035
Passive 1 1 1
Active 0.66 (0.15–2.92) 0.41 (0.10–1.66) 5.15 (1.16–22.79)

ART, antiretroviral therapy; CI, confidence interval.a Odds ratios were calculated using multivariable random-effects logistic regression, and hazard ratios were calculated using multivariable Weibull proportional hazard models incorporating the competing risks of death and loss to follow-up. Models were adjusted for the variables listed in Table 4 and for age, sex, year of starting ART, initial ART regimen, baseline CD4-cell count and clinical stage.b P-values were calculated using the Wald test.

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