Bulletin of the World Health Organization

Neonatal mortality, risk factors and causes: a prospective population-based cohort study in urban Pakistan

Imtiaz Jehan, Hillary Harris, Sohail Salat, Amna Zeb, Naushaba Mobeen, Omrana Pasha, Elizabeth M McClure, Janet Moore, Linda L Wright & Robert L Goldenberg

Volume 87, Number 2, February 2009, 130-138

Table 3. Clinical and delivery variables for infants who died within 28 days postpartum and for those who survived in prospective study of neonatal mortality in an urban Pakistani population, 2003–2005

Variables Death within 28 days (n = 53) Surviving infant(n = 1066) RR (95% CI)
No. (%)a No. (%)a
Gestational age at birth (n = 1119)
< 37 weeks 31 (58.5) 189 (17.7) 5.8 (3.4–9.7)
≥ 37 weeks (reference) 22 (41.5) 877 (82.3) 1.0 (NA)
Birth weight (n = 1021)
< 2000 g 6 (26.1) 55 (5.5) 5.6 (2.3–13.6)
≥ 2000 g (reference) 17 (73.9) 943 (94.5) 1.0 (NA)
Gender (n = 1055)
Male 22 (46.8) 521 (51.7) 0.8 (0.5–1.5)
Female (reference) 25 (53.2) 487 (48.3) 1.0 (NA)
Place of delivery (n = 1121)
Home 10 (18.9) 218 (20.3) 0.9 (0.5–1.8)
Hospital or other health-care facility (reference) 43 (81.1) 850 (79.6) 1.0 (NA)
Birth attendant (n = 1111)
Traditional birth attendant or other 6 (11.5) 175 (16.5) 0.6 (0.3–1.4)
Nurse, midwife or equivalent 9 (17.3) 256 (24.2) 0.6 (0.3–1.2)
Doctor (reference) 37 (71.2) 628 (59.3) 1.0 (NA)
Mode of delivery (n = 1068)
Vaginal (reference) 30 (63.8) 830 (81.3) 1.0 (NA)
Caesarean section 17 (36.2) 191 (18.7) 2.3 (1.3–4.2)
Preterm rupture of membranes (n = 1116)
< 12 hours (reference) 46 (90.2) 1000 (93.9) 1.0 (NA)
12–24 hours 5 (9.8) 65 (6.1) 1.6 (0.7–4.0)
Colour of amniotic fluid (n = 995)
Clear (reference) 28 (63.6) 793 (83.4) 1.0 (NA)
Meconium-stained 12 (27.3) 116 (12.2) 2.7 (1.4–5.3)
Other 4 (9.1) 42 (4.4) 2.5 (0.9–7.0)
Amniotic fluid odour (n = 975)
Foul-smelling 9 (23.8) 76 (7.8) 3.1 (1.5–6.2)
Not foul-smelling (reference) 32 (76.2) 858 (92.2) 1.0 (NA)
Prolonged labour (n = 1066)
Yes 4 (8.5) 137 (13.4) 0.6 (0.2–1.7)
No (reference) 43 (91.5) 882 (86.6) 1.0 (NA)
Vaginal bleeding (n = 1019)
Excessive 6 (13.3) 59 (6.0) 2.3 (1.0–5.1)
Normal (reference) 39 (86.7) 915 (94.0) 1.0 (NA)
Antepartum fever with chills (n = 1056)
Yes 7 (15.6) 90 (8.9) 1.9 (0.9–4.1)
No (reference) 38 (84.4) 921 (91.0) 1.0 (NA)

CI, confidence interval; NA, not applicable; RR, relative risk.
a Denominators for demographic and clinical characteristics may differ due to non-response.