Bulletin of the World Health Organization

Cost-effectiveness of malaria intermittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania

Guy Hutton, David Schellenberg, Fabrizio Tediosi, Eusebio Macete, Elizeus Kahigwa, Betuel Sigauque, Xavier Mas, Marta Trapero, Marcel Tanner, Antoni Trilla, Pedro Alonso & Clara Menendez

Volume 87, Number 2, February 2009, 123-129

Table 3. Cost-effectiveness of malaria IPTi in a study in Mozambique (Manhiça) and the United Republic of Tanzania (Ifakara), 2006

Cost-effectiveness ratiosa and ranges from Monte-Carlo simulation
Ifakara Manhiça
Using individual efficacy results
Cost per DALY averted 3.7 (1.6–12.2) 11.2 (3.6–92.0)
Cost per malaria episode averted 1.6 (0.8–4.0) 4.7 (1.7–30.3)
Cost per malaria death averted 100.2 (43.0–330.9) 301.1 (95.6–2498.4)
Using pooled efficacy results
Cost per DALY averted 7.9 (3.2–27.0) 8.3 (3.3–27.5)
Cost per malaria episode averted 3.3 (1.4–10.3) 3.5 (1.6–11.0)
Cost per malaria death averted 211.0 (84.5–730.2) 222.8 (88.6–747.1)

DALY, disability-adjusted life year; ITPi, intermittent preventive treatment in infants.
a Ratios represent the estimated aggregate effect of the IPTi intervention divided by the estimated aggregate cost (US$) of providing the intervention for a reference target population of 1000 immunized infants. The cost portion of the cost-effectiveness ratio includes only intervention costs; cost savings from fewer malaria cases are excluded.

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