Cost-effectiveness of oral cancer screening: results from a cluster randomized controlled trial in India
Sujha Subramanian, Rengaswamy Sankaranarayanan, Bela Bapat, Thara Somanathan, Gigi Thomas, Babu Mathew, Jissa Vinoda & Kunnambath Ramadas
Volume 87, Number 3, March 2009, 200-206
Table 4. Total cost and effectiveness of oral cancer screening per 100 000 individuals and cost-effectiveness of screening,a Trivandrum district, Kerala, India, 1996–2004
| Intervention arm (n = 87 829) | Control arm(n = 80 086) | Difference between intervention and control arms | ||||
|---|---|---|---|---|---|---|
| Total cost | ||||||
| Cost per 100 000 individuals (2004 US$) | 556 328 | 331 364 | 224 964 | |||
| Effectiveness | ||||||
| Number of cancer cases detected per 100 000 individuals | ||||||
| All individuals | 212.39 | 165.69 | 46.70 | |||
| High-risk individualsb | 420.65 | 396.70 | 23.95 | |||
| Number of cancer deaths per 100 000 individuals | ||||||
| All individuals | 79.78 | 91.24 | –11.46 | |||
| High-risk individualsb | 154.98 | 216.15 | –61.17 | |||
| Life-years saved per 100 000 individualsc | ||||||
| All individuals | NA | NA | 269.31d | |||
| High-risk individualsb | NA | NA | 1437.64d | |||
| Cost-effectiveness | ||||||
| Cost per additional cancer detected in the intervention arm relative to the control arm (2004 US$) | ||||||
| All individuals | NA | NA | 4817d | |||
| High-risk individualsb | NA | NA | 9394d | |||
| Cost per life-year saved by the intervention (2004 US$) | ||||||
| All individuals | NA | NA | 835d | |||
| High-risk individualsb | NA | NA | 156d | |||
NA, not available; US$, United States dollars.
a The cost-effectiveness of screening is expressed in terms of the cost per additional cancer detected and the cost per life-year saved.
b Users of tobacco or alcohol or both.
c Estimate based on an average life expectancy of 73.5 years and the assumption that death due to oral cancer will occur at an average age of 50 years.
d This figure was calculated based on the information provided in Table 3.