Bulletin of the World Health Organization

A comparison of two methods for measuring anti-hypertensive drug use: concordance of use with South African standard treatment guidelines

Thamizhanban Pillay, Anthony J Smith & Suzanne R Hill

Volume 87, Number 6, June 2009, 466-471

Table 2. Total cost of anti-hypertensive drugs in 16 hospitals in KwaZulu-Natal, South Africa, based on hospital prescription practices, versus total cost had hypertension treatment guidelines been followed

Anti-hypertensive drug Cost
(in US$a, per 100 prescriptions)b
Under current practice Under treatment guidelines
Diuretic 27.20 27.20 (1st line)
ACE inhibitor 67.25 15.07 (4th line)
CCB 86.33 57.55 (5th line)
Beta blocker 6.05 11.16 (3rd line)
Methyldopa 20.61
Reserpine 5.15 59.68 (2nd line)
Hydralazine 0.724
Total 213.30 170.67

ACE, angiotensin-converting enzyme; CCB, calcium channel blocker.
a 1 United States dollar (US$) = 10 South African rands.
b A prescription for a single patient may contain one or more drugs.