Bulletin of the World Health Organization

Structured approaches for the screening and diagnosis of childhood tuberculosis in a high prevalence region of South Africa

Mark Hatherill, Monique Hanslo, Tony Hawkridge, Francesca Little, Lesley Workman, Hassan Mahomed, Michele Tameris, Sizulu Moyo, Hennie Geldenhuys, Willem Hanekom, Lawrence Geiter & Gregory Hussey

Volume 88, Number 4, April 2010, 312-320

Table 4. Observed agreementa among nine structured approaches for diagnosing tuberculosis, South Africa, 2001–2006

System MASA Migliori SATVI Osborne Stoltz–Donald Kibel Fourie WHO–Harries Stegen–Toledo No. (%) diagnosed with tuberculosis
MASA 65.2 55.7 17.7 78.0 36.8 69.9 87.3 53.4 99 (6.9)
Migliori 0.19 72.7 51.1 71.0 61.3 68.3 64.4 85.3 602 (41.7)
SATVI 0.13 0.46 58.3 77.7 67.3 58.8 54.9 76.4 739 (51.1)
Osborne 0.02 0.13 0.15 37.9 76.9 38.6 20.6 61.9 1289 (89.2)
Stoltz–Donald 0.31 0.38 0.56 0.07 53.8 62.6 69.4 70 417 (28.9)
Kibel 0.06 0.27 0.34 0.33 0.21 52.7 39.2 70.7 1011 (70.0)
Fourie 0.09 0.32 0.18 0.06 0.10 0.18 73.8 59.0 440 (30.4)
WHO–Harries 0.18 0.18 0.11 0.02 0.08 0.08 0.24 53.4 145 (10.0)
Stegen–Toledo 0.12 0.71 0.53 0.19 0.42 0.38 0.20 0.12 772 (53.4)
No. (%) diagnosed with tuberculosis 99 (6.9) 602 (41.7) 739 (51.1) 1289 (89.2) 417 (28.9) 1011 (70.0) 440 (30.4) 145 (10.0) 772 (53.4) 1445 (100)

Κ, kappa statistic; MASA, Medical Association of South Africa; SATVI, South African Tuberculosis Vaccine Initiative; WHO, World Health Organization.
a Observed percentage agreement for paired individual observations (n = 1445) is above diagonal spaces; Κ values are below diagonal spaces.

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