Home visits by community health workers to prevent neonatal deaths in developing countries: a systematic review
Siddhartha Gogia & Harshpal Singh Sachdev
Volume 88, Number 9, September 2010, 658-666B
Table 4. Subgroup analysesa for relative risk (RR) of neonatal death in trials of home-based interventions to reduce neonatal and infant deaths and stillbirths, as identified through systematic review
| Stratification variable | No. of trials | Random effects model |
Fixed effects model |
Tests for heterogeneity |
P for heterogeneity in subgroups | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| RR | 95% CI | RR | 95% CI | I2 (%) | Q | |||||
| Overall | 5 | 0.62 | 0.44–0.87 | 0.62 | 0.55–0.70 | 86.4 | 29.45 | NA | ||
| Randomization | 0.006 | |||||||||
| Adequate | 2 | 0.54 | 0.39–0.75 | 0.52 | 0.43–0.62 | 63.6 | 2.75 | |||
| Inadequate | 3 | 0.67 | 0.40–1.13 | 0.73 | 0.62–0.86 | 89.6 | 19.16 | |||
| Type of care | 0.088 | |||||||||
| Preventive | 3 | 0.70 | 0.44–1.12 | 0.66 | 0.57–0.76 | 91.0 | 22.26 | |||
| Preventive and curative (injectable antibiotics) | 2 | 0.51 | 0.30–0.85 | 0.52 | 0.40–0.66 | 76.7 | 4.29 | |||
| Coverage (%) of home visits | < 0.001 | |||||||||
| < 50% | 1 | 1.06 | 0.81–1.38 | 1.06 | 0.81–1.38 | NA | ||||
| ≥ 50% | 4 | 0.54 | 0.42–0.70 | 0.54 | 0.47–0.62 | 70.1 | 10.05 | |||
CI, confidence interval; NA, not applicable; RR, relative risk.
a Subgroup analysis not done for baseline mortality, as all trials had high baseline mortality rates (> 45 per 1000 live births).