Can pharmacogenomics improve malaria drug policy?
Mary W Roederer, Howard McLeod & Jonathan J Juliano
Volume 89, Number 11, November 2011, 838-845
Table 3. Potential drug–gene relationships for first-line treatments of uncomplicated falciparum malaria in non-pregnant adults
| Drug | Gene |
|---|---|
| Artesunate | CYP2B6 |
| UGT1A9 | |
| UGT2B7 | |
| Artemether | CYP3A4/5 |
| CYP2C8 | |
| UGT1A9 | |
| UGT2B7 | |
| Amodiaquine | CYP2C8 |
| ABCB1 | |
| Mefloquine | ABCB1 |
| Sulfadoxine/pyrimethamine | No data |
| Lumefantrine | No data |