Bulletin of the World Health Organization

Accounting for model uncertainty in estimating global burden of disease

David M Vock, Elizabeth A Atchison, Julie M Legler, David RJ McClure, Jamie C Carlyle, Elysia N Jeavons & Anthony H Burton

Volume 89, Number 2, February 2011, 112-120

Table 1. Cut-off points for each stratum used to group countries and studies for the random-effects meta-analysis of child deaths from rotavirus infection

Variable Stratum
1 2 3 4 5
WHO model: under-5 mortality & geographical region Member States in all regions with very low mortality Member States in all regions with low mortality Member States in the Americas with high mortality Member States in Asia with high mortality Member States in Africa with high mortality
No. of countries with studies/no. of studies conducted/no. of countries in stratum 9/14/34 19/41/88 1/1/6 2/8/13 8/12/51
Alternative WHO model: under-5 mortality & geographical region Member States in all regions with very low mortality Member States in all regions with low mortality except the Americas Member States in the Americas with low or high mortality Member States in Asia with high mortality Member States in Africa with high mortality
No. of countries with studies/no. of studies conducted/no. of countries in stratum 9/14/34 14/29/62 6/13/32 2/8/13 8/12/51
Life expectancy at birth in females (years) > 76 66–75 53–65 46–53 34–45
No. of countries with studies/no. of studies conducted/no. of countries in stratum 18/30/63 11/26/66 3/10/33 5/7/16 2/3/14
Life expectancy at birth in males (years) > 76 70–75 65–69 50–64 36–49
No. of countries with studies/no. of studies conducted/no. of countries in stratum 7/12/28 11/22/39 11/20/48 5/12/49 5/8/28
Under-5 mortality rate (per 1 000 live births) 3–10 11–20 21–35 36–85 > 86
No. of countries with studies/no. of studies conducted/no. of countries in stratum 14/21/44 5/11/31 9/22/29 4/11/37 7/11/51
Infant mortality rate (per 1 000 live births) 2–7 8–17 18–30 31–75 > 76
No. of countries with studies/no. of studies conducted/no. of countries in stratum 11/20/36 9/15/38 8/19/34 5/13/38 6/9/46
% DPT3 immunization coverage among 1-year-olds 97–99 93–96 86–92 76–85 < 75
No. of countries with studies/no. of studies conducted/no. of countries in stratum 9/13/54 11/21/31 7/18/32 6/11/35 6/13/40
Natural log of per capita GNI (in PPP international dollars) > 9.50 8.75–9.49 8.00–8.74 7.25–7.99 < 7.24
No. of countries with studies/no. of studies conducted/no. of countries in stratum 12/21/45 11/18/42 7/20/38 4/9/38 5/8/29
% urban population 80.0–100.0 60.0–79.9 45.0–59.9 30.0–44.9 < 30.0
No. of countries with studies/no. of studies conducted/no. of countries in stratum 11/23/35 12/17/50 8/13/42 4/11/35 4/12/30

DTP3, third dose of diphtheria–tetanus–pertussis vaccine; GNI, gross national income; log, logarithm; PPP, purchasing power parity; WHO, World Health Organization.

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