Bulletin of the World Health Organization

Potential impact of single-risk-factor versus total risk management for the prevention of cardiovascular events in Seychelles

Roger Ndindjock, Jude Gedeon, Shanthi Mendis, Fred Paccaud & Pascal Bovet

Volume 89, Number 4, April 2011, 286-295

Table 1. Relative risk of fatal and non-fatal cardiovascular (CV) events associated with the use of selected CV risk management strategies, Seychelles

Management strategy and medication RRa
Stroke CEb CV eventc
Single-risk-factor
Serum cholesterol ≥ 6.2 mmol/l
   Statin 0.92 0.73 0.86
Blood pressure ≥ 140/90 mmHg
   Three classes of drugs 0.67 0.76 0.70
Total CV risk 0.84 0.68 0.79
   Aspirin 0.52 0.38 0.47
   Polypilld

CE, coronary event; RR, relative risk.

a See text for explanations and references underlying the RR estimates provided in this table. The RR of experiencing a CV event was calculated from the risk factor reductions obtained with the low-dose polycap. An incidence ratio of stroke to coronary events of 2:1 was assumed.18

b Includes unstable angina and myocardial infarction.

c Includes both stroke and coronary events.

d Composed of aspirin, a statin, a diuretic and an angiotensin-converting enzyme inhibitor.