Bulletin of the World Health Organization

Electronic monitoring of treatment adherence and validation of alternative adherence measures in tuberculosis patients: a pilot study

Jossy van den Boogaard, Ramsey A Lyimo, Martin J Boeree, Gibson S Kibiki & Rob E Aarnoutse

Volume 89, Number 9, September 2011, 632-639

Table 2. Median monitored treatment days and adherence rates, and proportions of patients who were less than 100%, 95% and 80% adherent,a as assessed by the Medication Event Monitoring System (MEMS), United Republic of Tanzania, 2010

Patientsa Monitored days
Adherence rate (%)
< 100% adherent
< 95% adherent
< 80% adherent
Median (IQR)b Median (IQR)b No. (%) No. (%) No. (%)
All (47) 168 (138–172) 98.4 (95.7–100) 33 (70) 10 (21) 1 (2)
Completed treatment (37) 169 (168–180.5) 98.4 (95.7–100) 27 (73) 7 (19) 0 (0)
Defaulters (2) 40.0/113c 50.0/100d 1 (50) 1 (50) 1 (50)
Deaths (4) 63 (29.5–104) 98.4 (95.6–99.6) 3 (75) 1 (25) 0 (0)
Study drop outs (4) 33 (21–73) 98.3 (88.4–100) 2 (50) 1 (25) 0 (0)

IQR, interquartile range.

a Only patients for whom MEMS data were available are included.

b All values given are medians and IQRs except for the values of the two defaulters.

c Number of monitored days for defaulter 1 and defaulter 2, respectively.

d Adherence rates of defaulter 1 and defaulter 2, respectively.