Elimination of paediatric HIV in KwaZulu-Natal, South Africa: large-scale assessment of interventions for the prevention of mother-to-child transmission
Christiane Horwood, Kerry Vermaak, Lisa Butler, Lyn Haskins, Sifiso Phakathi & Nigel Rollins
Volume 90, Number 3, March 2012, 168-175
Table 3. Association between mother-to-child transmission of HIV and antiretroviral regimens taken in pregnancy, KwaZulu-Natal, South Africa, 2008–2009 (n = 2858)
|Regimena||Infants with anti-HIV antibodiesb
|No. tested by PCR||Found PCR-positive for HIV DNA
|No antiretroviral prophylaxisc||68||11||16.2||–||–||–|
|Nevirapine and zidovudine||2089||118||5.7||0.30||0.14–0.66||0.003|
ART, antiretroviral treatment; CI, confidence interval; DNA, deoxyribonucleic acid; HIV, human immunodeficiency virus; OR, odds ratio; PCR, polymerase chain reaction.
a Mothers were allocated to regimen groups irrespective of the reported duration of each antiretroviral intervention.
b The infants tested were aged 4–8 weeks.
c Reference category.