Integrating antiretroviral therapy into antenatal care and maternal and child health settings: a systematic review and meta-analysis
Amitabh B Suthar, David Hoos, Alba Beqiri, Karl Lorenz-Dehne, Craig McClure & Chris Duncombe
Volume 91, Number 1, January 2013, 46-56
Table 1. Studies that met inclusion criteria in systematic review of the literature on the integration of antiretroviral therapy (ART) into maternal and child health services
| Author (year) | Population | Intervention | Comparator | Providers initiating ART | Losses to follow-up | Variables included in study model |
|---|---|---|---|---|---|---|
| Christie (2008) |
351 Jamaican women attending ANC clinics in Kingston, St Andrew and St Catherine, Jamaica | (i) Leadership, mentoring and training to health-care workers; (ii) implementing unified programme for the PMTCT of HIV infection; (iii) establishing unified maternal and infant treatment and care programme; (iv) building outcomes-based research agenda; (v) expanding programme | Intervention progress was measured over 5 years | Not reported | Not reported | None |
| Killam (2010) |
31 536 Zambian women attending eight public sector clinics in Lusaka district, Zambia | ART was provided in the ANC clinic to eligible women | ART-eligible women were referred urgently to an ART clinic located on the same premises as the ANC clinic but physically separate and separately staffed | Clinical officer (undefined) | 10.8% in intervention arm; 6.8% in the comparator arm | Clinic site cluster and time effects |
| Pfeiffer (2010) |
ART was integrated and decentralized into 67 Mozambique health-care sites, including ANC clinics | (i) Location of different services within the same facility; (ii) training of staff to provide multiple services; (iii) provision of tools, processes and training to better link separate services; (iv) strengthening of linkages, referral and follow-up between facility levels; (v) harmonization of logistics systems | From 2001–2005 Mozambique used a vertical day hospital model in which new, freestanding HIV treatment hospitals were constructed in large population centres alongside existing hospital compounds | ART providers (undefined) | 70% in comparator arm; 25% in intervention arm | None |
| Tsague |
938 pregnant women received care at 18 full package sites and the 14 stand-alone sites in Rwanda | Full package sites provided PMTCT and ART services at the same site | Stand-alone sites referred ART-eligible women to the nearest ART site | Physicians | Not reported | None |
ANC, antenatal care; ART, antiretroviral therapy; HIV, human immunodeficiency virus; PMTCT, prevention of mother-to-child transmission.