Timing of antiretroviral therapy in Cambodian hospital after diagnosis of tuberculosis: impact of revised WHO guidelines
Kimcheng Choun, Reaksmey Pe, Sopheak Thai, Natalie Lorent, Lutgarde Lynen & Johan van Griensven
Volume 91, Number 3, March 2013, 195-206
Table 1. Baseline characteristics of individuals with tuberculosis and HIV co-infection, pre- and post-implementation of the 2010 WHO ART guidelines, Cambodia, December 2008 to November 2011
| Characteristic | Beforea (n = 262) | Afterb (n = 190) | P |
|---|---|---|---|
| Sex, no. (%) | |||
| Female | 115 (43.9) | 89 (46.8) | 0.534 |
| Male | 147 (56.1) | 101 (53.2) | |
| Age (years), median (IQR) | 36 (30.2–41.7) | 38 (31.8–44.7) | 0.022 |
| ≤ 35, no. (%) | 125 (47.7) | 72 (37.9) | 0.038 |
| > 35, no. (%) | 137 (52.3) | 118 (62.1) | |
| Body weight (kg); (n = 443) | 46 (41–52) | 46 (40–53) | 0.681 |
| > 50, no. (%) | 161 (61.9) | 119 (65.0) | 0.505 |
| ≤ 50, no. (%) | 99 (38.1) | 64 (35.0) | |
| CD4+ cell count (cells/µL) at tuberculosis diagnosis, median (IQR) | 59 (18–168) | 43 (20.0–162.5) | 0.572 |
| > 50, no. (%) | 130 (49.6) | 82 (43.2) | 0.096 |
| ≤ 50, no. (%) | 104 (39.7) | 94 (49.5) | |
| Missing, No. (%) | 28 (10.7) | 14 (7.4) | |
| Type of tuberculosis, no. (%) | |||
| Extrapulmonary | 135 (51.5) | 92 (48.4) | 0.753 |
| Smear-positive pulmonary | 55 (21.0) | 40 (21.1) | |
| Smear-negative pulmonary | 72 (27.5) | 58 (30.5) | |
| Enrolled in HIV care before tuberculosis diagnosis, no. (%) | |||
| No | 107 (40.1) | 125 (65.8) | < 0.001 |
| Yes | 155 (59.2) | 65 (34.2) | |
| Initiated on ART, no. (%) | |||
| Total | 210 (80.1) | 152 (80.0) | 0.978 |
| Within 6 months after tuberculosis diagnosis | 197 (75.2) | 151 (79.5) | 0.286 |
ART, antiretroviral therapy; HIV, human immunodeficiency virus; IQR, interquartile range; WHO, World Health Organization.
a December 2008 to May 2010.
b June 2010 to November 2011.