Bulletin of the World Health Organization

Interventions for common perinatal mental disorders in women in low- and middle-income countries: a systematic review and meta-analysis

Atif Rahman, Jane Fisher, Peter Bower, Stanley Luchters, Thach Tran, M Taghi Yasamy, Shekhar Saxena & Waquas Waheed

Volume 91, Number 8, August 2013, 593-601I

Table 3. Outcomes of interest, effect measures and effect sizes from studies of interventions for common perinatal mental disorders among women in low- and middle-income countries

Outcome of interest No. of trials No. of participants Effect measure Effect size
Maternal depression 13a 15 429 SMD (95% CI) –0.38 (–0.56 to –0.21)
At 3 or 4 months postpartum 5 943 SMD (95% CI) –0.59 (–0.95 to –0.24)
At 6 months postpartum 7 1945 SMD (95% CI) –0.27 (–0.50 to –0.05)
At 12 months postpartum 2 12 541 SMD (95% CI) –0.19 (–0.36 to –0.04)
Infant health and development 6b 14 029 SMD (95% CI) Separate dimensions onlyc
Infant growth 3 1125 SMD (95% CI) 0.19 (0.07 to 0.31)
Infant development 2 473 SMD (95% CI) 1.57 (0.28 to 2.85)
Infant infectious disease rate 1 705 OR (95% CI) 0.60 (0.39 to 0.98)
Neonatal mortality rate 1 12 431 OR (95% CI) 0.68 (0.59 to 0.78)
Mother–infant relationship 4 1123 SMD (95% CI) 0.36 (0.22 to 0.51)

CI, confidence interval; OR, odds ratio; SMD, standardized mean difference.

a There are 14 outcomes because among trials in which maternal depression was an outcome of interest, one collected data at two time points, each reported in separate papers.

b There are seven outcomes because among trials presenting infant health and development outcomes, one reported two outcomes.

c Since diverse infant outcomes were assessed, they cannot be combined and are reported separately.