Bulletin of the World Health Organization

Diarrhoea-related hospitalizations in children before and after implementation of monovalent rotavirus vaccination in Mexico

Marcelino Esparza-Aguilar, Paul A Gastañaduy, Edgar Sánchez-Uribe, Rishi Desai, Umesh D Parashar, Vesta Richardson & Manish Patel

Volume 92, Number 2, February 2014, 117-125

Table 1. Annual rates of diarrhoea-related hospitalizations in children younger than 5 years, Mexico, 2003–2011

Socioeconomic categorya Age (months) Vaccine coverageb (%) No. of DR hospitalizationsc
Rate reductiond % (95%CI)
2003–2006 2008–2011
High ≤ 11 100 823 400 51 (48–54)
12–23 100 2050 1049 49 (45–53)
24–59 88 792 698 12 (4–19)
0–59 93 1001 597 40 (38–43)
Intermediate ≤ 11 84 580 302 48 (44–51)
12–23 100 2200 1113 49 (45–53)
24–59 79 850 638 25 (18–31)
0–59 86 834 497 41 (38–43)
Low ≤ 11 85 668 401 40 (36–44)
12–23 100 2703 1531 43 (39–47)
24–59 51 1077 893 17 (10–23)
0–59 71 1033 705 32 (29–34)
All ≤ 11 89 684 358 48 (46–50)
12–23 100 2301 1195 48 (46–50)
24–59 69 888 733 18 (13–21)
0–59 82 945 590 38 (36–39)

CI, confidence interval; DR, diarrhoea-related; RVA, species A rotavirus.

a The socioeconomic status of the state in which the reporting hospital was located, based on the human development index of the state for the year 2007.

b RVA vaccine coverage with two doses, as recorded in 2010. As the Ministry of Health may deliver vaccine to a region larger than that planned, the recorded coverage, which is based on the size of the planned target population, can exceed 100%.

c Per 10 000 all-cause admissions. Prevaccine and postvaccine rates – shown for 2003–2006 and 2008–2011, respectively – are based on the sums of the monthly median numbers of diarrhoea-related hospitalizations and all-cause admissions at 346 health ministry hospitals. To account for differences in vaccine coverage by age group and postvaccine year, the postvaccine values for children aged ≤ 11, 12–23 and 24–59 months were based on the number of diarrhoea-related hospitalizations over 2008–2011, 2009–2011 and 2010–2011, respectively.

d Rate reduction in the postvaccine period with respect to the prevaccine period.