Buruli ulcer

Role of specific antibiotics in Mycobacterium ulcerans (Buruli ulcer) management

Provisional guidelines

Antibiotics administration and dosages

Usual doses are:

  • rifampicin, 10 mg/kg body weight by mouth daily for 8 weeks;
  • streptomycin, 15 mg/kg body weight by intramuscular injection daily for 8 weeks.

Further details are given in Table I and Annex I.

Table 1: Rifampicin and streptomycin dosage according to patient body weighta

a Adapted from (25).
b Syrup form may be used for children.
c Contraindicated during pregnancy.