Buruli ulcer

Prof. Gerd Pluschke

Nationality: German

E-mail: Gerd.Pluschke@unibas.ch

Present positions

  • Head Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland
  • Professor in Infection biology and immunology, University of Basel, Switzerland

Areas of expertise/interest

  • Research in infection biology focusing on host–pathogen interactions, molecular epidemiology, immunology and vaccine design
  • Research activities on Buruli ulcer in the fields of molecular epidemiology, transmission, immunology, treatment and diagnosis

Recent publications

  • Qi W, Käser M, Röltgen K, Yeboah-Manu D, Pluschke G. Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing. PLoS Pathog. 2009 Sep;5(9):e1000580. Epub 2009 Sep 11. [Abstract/Free full text]
  • Käser M, Hauser J, Pluschke G. Single nucleotide polymorphisms on the road to strain differentiation in Mycobacterium ulcerans. J Clin Microbiol. 2009 Nov;47(11):3647-52. Epub 2009 Sep 2. [Abstract/Free full text]
  • Käser M, Gutmann O, Hauser J, Stinear T, Cole S, Yeboah-Manu D, Dernick G, Certa U, Pluschke G. Lack of insertional-deletional polymorphism in a collection of Mycobacterium ulcerans isolates from Ghanaian Buruli ulcer patients. J Clin Microbiol. 2009 Nov;47(11):3640-6. Epub 2009 Sep 2. [Abstract/Free full text]
  • Käser M, Hauser J, Small P, Pluschke G. Large sequence polymorphisms unveil the phylogenetic relationship of environmental and pathogenic mycobacteria related to Mycobacterium ulcerans. Appl Environ Microbiol. 2009 Sep;75(17):5667-75. Epub 2009 Jul 10. [Abstract/Free full text]
  • Braxmeier S, Hellmann M, Beck A, Umboock A, Pluschke G, Junghanss T, Weinlaeder H. Phase change material for thermotherapy of Buruli ulcer: modelling as an aid to implementation. J Med Eng Technol. 2009;33(7):559-66. [Abstract/Free full text]
  • Schütte D, Pluschke G. Immunosuppression and treatment-associated inflammatory response in patients with Mycobacterium ulcerans infection (Buruli ulcer). Expert Opin Biol Ther. 2009 Feb;9(2):187-200. [Abstract/Free full text]
  • Junghanss T, Um Boock A, Vogel M, Schuette D, Weinlaeder H, Pluschke G. Phase Change Material for Thermotherapy of Buruli Ulcer: A Prospective Observational Single Centre Proof-of-Principle Trial. PLoS Negl Trop Dis. 2009;3(2):e380. Epub 2009 Feb 17. [Abstract/Free full text]
  • Huygen K, Adjei O, Affolabi D, Bretzel G, Demangel C, Fleischer B, Johnson RC, Pedrosa J, Phanzu DM, Phillips RO, Pluschke G, Siegmund V, Singh M, van der Werf TS, Wansbrough-Jones M, Portaels F. Buruli ulcer disease: prospects for a vaccine. Med Microbiol Immunol. 2009 May;198(2):69-77. Epub 2009 Feb 7. [Abstract/Free full text]
  • Käser M, Pluschke G. Differential Gene Repertoire in Mycobacterium ulcerans Identifies Candidate Genes for Patho-Adaptation. PLoS Negl Trop Dis. 2008;2(12):e353. Epub 2008 Dec 23. [Abstract/Free full text]
  • Schütte D, Umboock A, Pluschke G. Phagocytosis of Mycobacterium ulcerans in the course of rifampicin and streptomycin chemotherapy in Buruli ulcer lesions. Br J Dermatol. 2009 Feb;160(2):273-83. Epub 2008 Oct 22. [Abstract/Free full text]