CHOosing Interventions that are Cost Effective (WHO-CHOICE)

Published Papers


Earlier publications (2001 - 2007)


The burden and costs of chronic diseases in low-income and middle-income countries
Abegunde D, Mathers C, Adam T, Ortegon M, Strong K
Lancet, 370: 1928-1938 (2007)


Chronic disease prevention: health effects and financial costs of strategies to reduce salt intake and control tobacco use
Asaria P, Chisholm D, Mathers C, Ezzati M, Beaglehole R
Lancet, 370: 1944-1953 (2007)


Prevention of cardiovascular disease in high-risk individuals in low-income and middle-income countries: health effects and costs
Lim SS, Gaziano TA, Gakidou E, Reddy KS, Farzadfar F, Lozano R, Rodgers A
Lancet, 370: 1954-1962 (2007)


Economic evaluation in health: saving money or improving care?
Chisholm D, Evans D
Journal of Medical Economics, 10: 325-337 (2007)


Cost of scaling-up mental health care in low- and middle-income countries
Chisholm D, Lund , Saxena S
British Journal of Psychiatry, 191: 528-535 (2007)


Scaling-up services for mental disorders: a call for action
Chisholm D, Flisher AJ, Lund C, Patel V, Saxena S, Thornicroft G, Tomlinson M; Lancet Global Mental Health Group
Lancet, 370: 1241-1252 (2007)


Cost-effectiveness of an essential mental health intervention package in Nigeria
Gureje O, Chisholm D, Kola L, Lasebikan V, Saxena S
World Psychiatry, 6: 42-48 (2007)


Costs, health effects and cost-effectiveness of alcohol and tobacco control strategies in Estonia
Lai T, Habicht J, Reinap M, Chisholm D, Baltussen R
Health Policy, 84: 75-88 (2007)


Estimated global resources needed to attain international malaria control goals
Kiszewski A, Johns B, Schapira A, Delacollette C, Crowell V, Tan-Torres T, Ameneshewa B, Teklehaimanot A, Nafo-Traore F.
Bulletin of the World Health Organization, 85: 623-630(2007)


What will it cost to attain the health MDGs?
Nordstrom A, Tan Torres Edejer T, Evans D
Bulletin of the World Health Organization, 85: 246 (2007)


Estimated global resources needed to attain universal coverage of maternal and newborn health services
Johns B, Sigurbjörnsdóttir K, Fogstad H, Zupan J, Mathaid M, Tan-Torres Edejer T
Bulletin of the World Health Organization, 85: 256-263 (2007)


A financial road map to scaling up essential child health interventions in 75 countries
Stenberg K, Johns B, Scherpbier RW, Tan Torres Edejer T
Bulletin of the World Health Organization, 85: 305-314 (2007)


Costs of scaling up health interventions: a systematic review
Johns B, Tan Torres Edejer T, WHO-CHOICE
Health Policy and Planning, 20 (1): 1-13 (Jan 2005)

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Enhancing the comparability of costing methods: cross-country variability in the prices of non-traded inputs to health programmes
Johns B, Adam T, Evans DB
Cost Effectiveness and Resource Allocation, 4: 8 (2006)


Determinants of variation in the cost of inpatient stays versus outpatient visits in hospitals: a multi-country analysis
Adam T, Evans D
Social Science and Medicine, 63: 1700-1710 (2006)


Priority setting of public spending in developing countries: Do not try to do everything for everybody
Baltussen R
health Policy, 78: 149-156 (2006)


Comparative cost-effectiveness of policy instruments for reducing the global burden of alcohol, tobacco and illicit drug use
Chisholm D, Doran C, Shibuya K, Rehm J
Drug and Alcohol Review, 25: 553-565 (2006)


Time to reassess strategies for improving health in developing countries
Evans DB, Adam T, Tan-Torres Edejer T, Lim S, Cassels A, Evand TG for the WHO CHOICE MDG Team
British Medical Journal, 331: 1133-1136 (Nov 11, 2005)


Methods to assess the costs and health effects of interventions for improving health in developing countries
Evans DB, Tan-Torres Edejer T, Adam T, Lim S for the WHO CHOICE MDG Team
British Medical Journal, 331: 1137-1140 (Nov 11, 2005)


Evaluation of current strategies and future priorities for improving health in developing countries
Evans DB, Lim S, Adam T, Tan-Torres Edejer T, for the WHO CHOICE MDG Team
British Medical Journal, doi 10.1136/bmj.38658.675243.94 (Nov 10, 2005)


Cost effectiveness analysis of strategies to combat HIV/AIDS in developing countries
Hogan DR, Baltussen R, Hayashi C, Lauer J, Salomon JA
British Medical Journal, doi 10.1136/bmj.38643.368692.68 (Nov 10, 2005)


Cost effectiveness analysis of strategies for tuberculosis control in developing countries
Baltussen R, Floyd K, Dye C
British Medical Journal, doi 10.1136/bmj.38645.660093.68 (Nov 10, 2005)


Cost effectiveness analysis of strategies to combat malaria in developing countries
Morel CM, Lauer J, Evans D
British Medical Journal, doi 10.1136/bmj.38639.702384.AE (Nov 10, 2005)


Cost effectiveness analysis of strategies for child health in developing countries
Tan-Torres Edejer T, Aikins M, Black R, Wolfson L, Hutubessy R, Evans D
British Medical Journal, doi 10.1136/bmj.38652.550278.7C (Nov 10, 2005)


Cost effectiveness analysis of strategies for maternal and neonatal health in developing countries
Adam T, Lim S, Mehta S, Bhutta ZA, Fogstad H, Mathai M, Zupan J, Darmstadt GL
British Medical Journal, 331: 1107 (Nov 11, 2005)


Evidence-based, cost-effective interventions: how many newborn babies can we save?
Darmstadt GL, Bhutta ZA, Cousens S, Adam T, Walker N, de Bernis L; Lancet Neonatal Survival Steering Team
The Lancet, 12;365(9463):977-88 (March 2005)

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Effectiveness and cost of facility based Integrated Management of Childhood Illness (IMCI) in Tanzania
Armstrong Schellenberg JR, Adam T, Mshinda H, Masanja H, Kabandi G, Mukasa O, John T, Charles S, Nathan R, Wilczynska K, Mgalula L, Mbuya C, Mswia R, Manzi F, de Savigny D, Schellenberg D, Victoria C
The Lancet, 364 (9445); 1583-1594 (Oct 30 2004)

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Does the Integrated Management of Childhood Illness Cost more than Routine Care? Results from Tanzania
Adam T, Manzi F, Armstrong Schellenberg J, Mgalula L, de Savigny D and Evans DB
Bulletin of the World Health Organization, 83(5) 369-77 (May 2005)

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Achieving the WHO/UNAIDS antiretroviral treatment 3 by 5 goal: what will it cost?
Gutierrez JP, Johns B, Adam T, Bertozzi SM, Edejer TT, Greener R, Hankins C, Evans DB
Lancet, 364: 9428 (Jul 3 2004)

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Costs and health effects of breast cancer interventions in epidemiologically different regions of Africa, North America and Asia
Groot MT, Baltussen RM, Uyl-de Groot CA, Anderson BO, Hortobagyi GN
The Breast Journal, 12(Suppl. 1): 80-91 (2006)


Cost-effectiveness of clinical interventions for reducing the global burden of bipolar disorder
Chisholm D, van Ommeren M, Ayuso-Mateos JL, Saxena S
British Journal of Psychiatry, 187: 559-567 (2005)

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Reducing the global burden of depression: Population-level analysis of intervention cost-effectiveness in 14 world regions
Chisholm D, Sanderson K, Ayuso-Mateos JL, Saxena S
British Journal of Psychiatry, 184: 393-403 (2004)

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    Full article available free if logging on from one of the 75 poorest nations.

Cost-effectiveness of first-line anti-epileptic drug treatments in the developing world: a population-level analysis
Chisholm D, on behalf of WHO-CHOICE
Epilepsia, 46 (5): 751-759(2005)

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Choosing cost-effective interventions in psychiatry; results from the CHOICE programme of the World Health Organization
Chisholm D
World Psychiatry, 4: 37-44 (2005)


Reducing the Global Burden of Hazardous Alcohol Use: A Comparative Cost-Effectiveness Analysis
Chisholm D, Rehm J, Van Ommeren M, Monteiro M
Journal of Studies on Alcohol (November 2004)


WHO Framework Convention on Tobacco Control: development of an evidence based global public health treaty
Shibuya K, Ciecierski C, Guindon E, Bettcher DW, Evans DB, Murray CJL
British Medical Journal, 327: 154-157 (July 19, 2003)

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Effectiveness and costs of interventions to lower systolic blood pressure and cholesterol: a global and regional analysis on reduction of cardiovascular-disease risk
Murray CJL, Lauer JA, Hutubessy RCW, Niessen L, Tomijima N, Rodgers A, Lawes CMM, Evans DB
The Lancet, 361: 717-725 (March 1, 2003)

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The Cost-Effectiveness of Policies for the Safe and Appropriate Use of Injection in Health Care Settings
Dziekan G, Chisholm D, Johns B, Rovira J, Hutin YJF
Bulletin of the World Health Organization, 81: 277-285 (2003)

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The health benefits to interventions to reduce indoor air pollution from solid fuel use: a cost-effectiveness analysis
Mehta S, Shahpar C
Energy for Sustainable Development, VIII (3): 53-59 (Sept 2004)

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Iron fortification and iron supplementation are cost-effective interventions to reduce iron deficiency in four subregions of the world
Baltussen R, Knai C, Sharan M
Journal of Nutrition, 134: 2678-2684 (Oct 2004)

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Cost-effectiveness analysis of cataract surgery: a global and regional analysis
Baltussen R, Sylla M, Mariotti SP
Bulletin of the World Health Organization, 82 (5): 338-345 (May 2004)


Generalized cost-effectiveness analysis for national-level priority-setting in the health sector
Hutubessy R, Chisholm D, Edejer TTT, WHO-CHOICE
Cost-effectiveness and Resource Allocation, 1: 8 (2003)


Generalized cost-effectiveness analysis: an aid to decision making in health
Hutubessy R.C., Baltussen, RMPM, Tan Torres-Edejer T, Evans DB
Applied Health Economics and Health Policy, 1:2, 39-46 (2002)



Cost valuation in resource-poor settings
Hutton G, Baltussen R
Health Policy and Planning, 20 (4): 252-259 (April 2005)

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Econometric estimation of country-specific hospital costs
Adam T, Evans D, Murray CJL
Cost-effectiveness and Resource Allocation, 1: 3 (2003)


Programme costs in the economic evaluation of health interventions
Johns B, Baltussen R, Hutubessy R
Cost-effectiveness and Resource Allocation, 1: 1 (2003)


Accounting for the cost of scaling-up health interventions
Johns B, Baltussen R
Health Economics, 13 (11): 1117-1124 (Nov 2004)

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PopMod: A longitudinal four-state population model with two disease states and comorbidity
Lauer JA, Murray CJL, Roehrich K, Wirth H
Cost-effectiveness and Resource Allocation, 1: 6 (2003)


Stochastic League Tables: Communicating Cost-Effectiveness Results to Decision-Makers
Hutubessy RCW, Baltussen RMPM, Evans DB, Barendregt JJ, Murray C
Health Economics, 10: 473-477 (2001)


Uncertainty in cost-effectiveness analysis: probablistic uncertainty analysis and stochastic league tables
Baltussen R, Hutubessy R, Evans D, Murray C
Int J Technol Assess Health Care, 18:1, 112-119 (Winter 2002)

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Critical issues in the economic evaluation of interventions against communicable diseases: a review
Hutubessy RCW, Bendib LM, Evans DB
Acta Tropica, 78:3, 191-206 (2001)

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Cost-effectiveness Analysis: Can we reduce variability in costing methods?
Adam T, Evans DB, Koopmanschap MA
International Journal of Technology Assessment in Health Care, 19:2, 407-420 (2003)

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Report on the methods used to estimate costs of reaching the WHO target of “3 by 5”
Adam, T, Bertozzi S, Edejer TT, Evans DB, Greener R, Gutierrez JP, Hankins C, Johns B, Meyer-Rath G
Report of the UNAIDS/WHO working group (December 2003)


Resource utilization for neuropsychiatric disorders in developing countries: a multinational Delphi consensus study
Ferri C, Chisholm D, Van Ommeren M, Prince M.
Social Psychiatry and Psychiatric Epidemiology, 39 (3): 218-227 (March 2004)

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Grading quality of evidence and strength of recommendations
Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O'Connell D, Oxman AD, Phillips B, Schunemann HJ, Edejer TT, Varonen H, Vist GE, Williams JW Jr, Zaza S; GRADE Working Group
British Medical Journal, 328 (7454): 1490 (June 19 2004)

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World health system performance revisited: the impact of varying the relative importance of health system goals
Lauer JA, Lovell CAK, Murray CJL, Evans DB
BioMed Central Health services Research, 4 (1): 19 (July 22 2004)

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Breastfeeding patterns and exposure to suboptimal breastfeeding among children in developing countries: review and analysis of nationally representative surveys
Lauer JA, Betran AP, Victoria CG, de Onis M, Barros AJ
BioMed Central Medicine, 2 (1): 26 (July 1 2004)

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Methods for the costing component of the Multi-country evaluation of Integrated Management of Childhood Illness (IMCI)
Adam T, Bishai D, Khan M, Evans DB
WHO Publication 2004


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