Cost effectiveness and strategic planning (WHO-CHOICE)

EMR B: Cost effectiveness results for Epilepsy

This Table provides summary results of the total population-level costs, effects and cost-effectiveness for the selected WHO sub-region and risk factor / disease for the year 2000.

I$ - International Dollars
Program Costs include costs of administration, media, training etc
Patient Costs include costs of hospital visits, drugs, etc
Incremental cost-effectiveness ratio (ICER) is defined as the incremental change in cost, divided by the incremental change in effectiveness. ICERs are reported for the successive set of interventions that would be selected at expanding levels of resource availability, starting with the intervention with the lowest cost per DALY averted, then moving to the next most cost-effective combination intervention out of the remaining available set of interventions.
Dominated is used to denote an intervention that is more costly and/or less effective than other, more efficient (single or combined) interventions; i.e. dominated interventions do not appear on the expansion path of most cost-effective strategies.

Interventions:Codes_and_Descriptions Coverage Cost per year (I$, millions) per one million_population [i.e. cost per capita] % Program costs % Patient costs DALYs averted per year per one million_population Average Cost per DALY averted Incremental Cost per DALY averted
EPI-1: Older anti-epileptic drug (phenobarbital) 50% 0.31 44% 56% 150 2,063 2,063
EPI-2: Older anti-epileptic drug (phenytoin) 50% 0.32 43% 57% 150 2,107 Dominated
EPI-3: Newer anti-epileptic drug (carbamazepine) 50% 0.37 37% 63% 150 2,471 Dominated
EPI-4: Newer anti-epileptic drug (valproic acid) 50% 0.47 29% 71% 150 3,118 Dominated
EPI-5: Older anti-epileptic drug (phenobarbital) 80% 0.55 49% 51% 237 2,308 2,732
EPI-6: Older anti-epileptic drug (phenytoin) 80% 0.56 49% 51% 237 2,354 Dominated
EPI-7: Newer anti-epileptic drug (carbamazepine) 80% 0.64 42% 58% 237 2,722 Dominated
EPI-8: Newer anti-epileptic drug (valproic acid) 80% 0.80 34% 66% 237 3,377 Dominated