Zika virus disease
A person presenting with rash and/or fever and at least one of the following signs or symptoms:
- arthralgia; or
- arthritis; or
- conjunctivitis (non-purulent/hyperaemic).
A suspected case with presence of IgM antibody against Zika virus1 and an epidemiological link2
A person with laboratory confirmation of recent Zika virus infection:
- presence of Zika virus RNA or antigen in serum or other samples (e.g. saliva, tissues, urine, whole blood); or
- IgM antibody against Zika virus positive and PRNT90 for Zika virus with titre ≥20 and Zika virus PRNT90 titre ratio ≥ 4 compared to other flaviviruses; and exclusion of other flaviviruses
1 With no evidence of infection with other flaviviruses
2 Contact with a confirmed case, or a history of residing in or travelling to an area with local transmission of Zika virus within two weeks prior to onset of symptoms.