Global Alert and Response (GAR)

WHO consultation on public health and animal Transmissible Spongiform Encephalopathies: Epidemiology, risk and research requirements. With the participation of the Office International des Epizooties. Geneva, Switzerland, 1-3 December 1999

WHO/CDS/CSR/APH/2000/2

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Consultation on Public Health and Animal Transmissible Spongiform Encephalopathies: Epidemiology, Risk and Research Requirements. With the participation of the Office International of Epizooties. Geneva, Switzerland, 1-3 December 1999

Opening

Section 1. Background
1.1 Trends in Bovine Spongiform Encephalopathy
1.2 Trends in variant Creutzfeldt Jakob Disease

Section 2. Bovine Spongiform Encephalopathy in Sheep
2.1 Transmission of Bovine Spongiform Encephalopathy into sheep: Experimental evidence and ongoing work in the United Kingdom
2.2 Estimating the epidemiology of Bovine Spongiform Encephalopathy in sheep
2.3 France: Status report on investigations of Bovine Spongiform Encephalopathy in sheep
2.4 Netherlands: Status report on investigations of Bovine Spongiform Encephalopathy in sheep
2.5 Spongiform Encephalopathy Advisory Committee - Risk assessment of Bovine Spongiform Encephalopathy in sheep
2.6 European Union - Risk assessment of Bovine Spongiform Encephalopathy in sheep
2.7 Office International des Epizooties - Measures relating to BSE

Section 3. Scrapie Elimination
3.1 Principles, practice and experience of scrapie elimination
3.2 Transmissible Spongiform Encephalopathies in sheep – Surveillance programmes
3.3 Breeding scrapie resistant sheep: The genetics of Transmissible Spongiform Encephalopathies in sheep
3.4 Industry and scrapie elimination: Perspective of the Scrapie Information Group
3.5 Animal vaccine-related Transmissible Spongiform Encephalopathy risks: Scrapie outbreak in Italy

Section 4. Chronic Wasting Disease
4.1 Epidemiology of Chronic Wasting Disease
4.2 Diagnosis and pathogenesis of Chronic Wasting Disease
4.3 Assessing interspecies Transmissible Spongiform Encephalopathy transmission using the cell-free conversion assay
4.4 Centers for Disease and Control and Prevention investigations relating to Chronic Wasting Disease exposures

Section 5. Feline Spongiform Encephalopathy
5.1 Pathology and epidemiology of Feline Spongiform Encephalopathy

Section 6. Transmissible Spongiform Encephalopathies in Other Species
6.1 Transmissible Spongiform Encephalopathies in captive wild bovids and felids
6.2 The implications to humans of zoo primates infected with Bovine Spongiform Encephalopathy
6.3 Are there prion diseases of fish?
6.4 The case for the zoonotic origins of Creutzfeldt-Jakob Disease

Section 7. Evaluation of Animal Transmissible Spongiform Encephalopathy Zoonotic Potential
7.1 Diagnostic tests for Transmissible Spongiform Encephalopathies: Status and update
of the European Union initiative
7.2 Potential of diagnostic tests to distinguish between Bovine Spongiform Encepathology and scrapie
7.3 Diagnostic protocols for Transmissible Spongiform Encephalopathies: Rationales and their applications
7.4 Diagnostic tests and standardized reagents: WHO initiative
7.5 The Rendering Industry – Current sourcing and current product uses in animals


7.6 Could vaccines prepared from animal brain tissue pose a risk of transmission of Transmissible Spongiform Encephalopathies to humans?
7.7 Surveillance and eradication of animal diseases: Principles from human diseases

Section 8. Recommendations

Annex 1 Agenda 

Annex 2 List of Participants

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