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The revision of the surveillance case definition for variant Creutzfeldt-Jakob Disease (vCJD). Report of a WHO consultation Edinburgh, United Kingdom 17 May 2001
WHO/CDS/CSR/EPH/2001/5
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The Revision of the Surveillance Case Definition for Variant Creutzfeldt-Jakob Disease (vCJD). Report of a WHO consultation Edinburgh, United Kingdom 17 May 2001
| Contents Abbreviations used Background The Consultation process Introduction Key elements in the diagnosis of vCJD I. Suspect vCJD: clinical diagnosis II. Probable vCJD The role of EEG in the diagnosis of vCJD The role of 14-3-3 in the diagnosis of vCJD Number of samples positive 14-3-3 /total samples investigated The role of Magnetic Resonance Imaging (MRI) in the diagnosis of vCJD The role of Tonsil Biopsy and Lymphoreticular Tissues in the diagnosis of vCJD III. Definite vCJD The role of neuropathology in the diagnosis of vCJD Suggested approaches to post-mortem examination Western blot analysis of PrP isotype in the diagnosis of vCJD Handling of instruments used to diagnose vCJD Annex I - Case Definition for vCJD Annex II - Agenda for the Consultation Annex III - List of Scientific Presentations to the Consultation Annex IV - Participants Annex V - Pathological Characteristic of vCJD (from 1998 WHO Consultation) Annex VI - EEG Criteria for sCJD Annex VII - List of WHO Reference Centres Annex VIII- Clinical Features of Variant CJD, Sporadic CJD and Suspect vCJD Cases with an Alternative Final Diagnosis Annex IX - Selected References |
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