Emergencies preparedness, response

Screening, assessment and management of neonates and infants with complications associated with Zika virus exposure in utero

Interim guidance


World Health Organization

Publication details

Number of pages: 15
Publication date: Updated 30 August 2016
Languages: English
WHO reference number: WHO/ZIKV/MOC/16.3 Rev.3


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This Rapid Advice Guideline updates the Interim Guidance on the “Assessment of infants with microcephaly in the context of Zika virus” published in February 2016 (WHO/ZIKV/MOC/16.3). The recommendations provides guidance on the screening, clinical assessment, neuroimaging, laboratory investigation and follow-up of children born to women living in areas of Zika virus transmission. The Guideline summarises the evidence base and rationale in support of the recommendations and expands the scope to address complications beyond microcephaly and what is now referred to as the congenital Zika virus syndrome.

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