This publication is currently under review and will be updated shortly.

Emergencies preparedness, response

Surveillance for Zika virus infection, microcephaly and Guillain-Barré syndrome

Interim guidance

World Health Organization

Publication details

Number of pages: 9
Publication date: Updated 7 April 2016
Languages: English
WHO reference number: WHO/ZIKV/SUR/16.2 Rev.1


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This document provides interim WHO recommendations for the surveillance of Zika virus and potentially related complications. It has been developed in consideration of the declaration on 1 February 2016 by the WHO Director-General of a Public Health Emergency of International Concern with regard to clusters of microcephaly and neurological disorders potentially associated with Zika virus.

This document provides interim recommendations for the surveillance of Zika virus infection, microcephaly and Guillain-Barré syndrome, in four different contexts and describes reporting requirements to WHO. Transmission refers to vector-borne transmission, unless specified differently. Autochthonous infection is considered to be an infection acquired in-country, i.e. among patients with no history of travel during the incubation period or who have travelled exclusively to non-affected areas during the incubation period. This document does not provide guidance on laboratory investigation or vector surveillance.

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