Diabetes

The guidelines development group for updating the WHO classification of hyperglycaemia and the diagnostic criteria for intermediate hyperglycaemia

WHO has previously published three technical reports and two guidelines on diagnosis and classification of diabetes (WHO 1965, WHO 1980, WHO 1985, WHO 1999, WHO/IDF 2006). In 2006 WHO, updated the section on definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia, but not the section on classification. The objectives of the guidelines are:

  • To determine whether a revision and/or refinement of the 1999 classification of hyperglycaemia is warranted based on new available evidence, and if necessary, to revise and/or refine the existing classification.
  • To review the current (2006) diagnostic cut-off levels for of plasma glucose and HbA1C for the diagnosis of intermediate hyperglycaemia. The revision will be based on:
    • The relationship between existing various plasma glucose and HbA1c cut-off values and the risk of developing diabetes, microvascular complications, CVD, as well as the risk of dying.
    • The effect of interventions (lifestyle, medication) on incidence of diabetes, microvascular complications, CVD, CVD mortality and all-cause mortality in people with intermediate hyperglycaemia as defined by the various cut-off values for plasma glucose and HbA1c.

The 2013 guidelines on the Classification and diagnosis of hyperglycaemia first detected in pregnancy will not be updated for this guideline.

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Contact: rogligc@who.int