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Drug resistance

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Antimicrobial Resistance

Antimicrobial agents are considered "miracle drugs" that are our leading weapons in the treatment of infectious diseases. Antimicrobial resistance is the ability of microorganisms to withstand attack by antimicrobials, and the growing rise in resistant pathogens threatens lives and wastes limited healthcare resources.

Microbes and Antimicrobial Agents

Antimicrobial agents are medicines used to treat infections by bacteria, fungi, parasites, and viruses. The discovery of antimicrobials is one of the most important advances in health in human history - decreasing suffering from disease and saving lives.

:: More information

The rise in resistant microorganisms

The use and misuse of antimicrobials over the past 70 years has led to a relentless rise in the number and types of microorganisms resistant to the action of these medicines - leading to death, increased suffering and disability, and higher healthcare costs.

:: Emergence and spread of antimicrobial resistance
:: Public health importance
:: Surveillance of antimicrobial resistance

What can be done?

Two factors drive the rise and spread of resistant microbes: 1. Overuse and misuse of antimicrobials and 2. the spread of resistant organisms between individuals, communities, and countries. Consequently, interventions are needed in two areas:

:: Improving antimicrobial use
:: Blocking transmission of resistant organisms

Containment of Antimicrobial Resistance

Urgent action is required at local, national, and international levels to ensure the adequate treatment of patients today and the preservation of the life-saving power of antimicrobials for future generations.

:: What WHO is doing
:: WHO Global Strategy for Containment of Antimicrobial Resistance
:: Global Patient Safety Challenge: Tackling Antimicrobial Resistance

WHO PROGRAMMES AND ANTIMICROBIAL RESISTANCE

:: Child and Adolescent Health and Development
:: Food Safety and Zoonoses
:: Global Malaria Programme
:: HIV/AIDS Department
:: Infection Control
:: Patient Safety
:: Reproductive Health and Research
:: Stop TB Department
DOCUMENTS AND PUBLICATIONS

- Antimicrobial Resistance Freqently Asked Questions (< 100K)
- Fact Sheet: Antimicrobial resistance (< 100K) (2002)
- Antimicrobial Resistance Document Centre

ANTIMICROBIAL RESISTANCE OUTSIDE OF WHO HEADQUARTERS

:: WHO Regional Offices
:: WHO Collaborating Centres
:: Other Organizations and Links


HIGHLIGHTS

Laboratory manual
Identification and antimicrobial susceptibility testing of important bacterial pathogens

Assessment tool for AMR surveillance networks
Assessment questionnaire


DISEASE OUTBREAKS

1996 - Global Cholera Update
22 January 1996

1996 - Dengue in the Americas
22 January 1996

1996 - Ebola infection in Côte d'Ivoire/Liberia
22 January 1996



Containing known risks
These activities are part of CSR's Global Strategy
Find out more


MORE INFORMATION

Weekly Epidemiological Record
Information on cases and outbreaks of infectious diseases

International travel and health
Health advice for travellers

Communicable Disease News
New report: Global defence against the infectious disease threat

Infectious diseases index