Fluid management in severely malnourished children under 5 years of age without shock
In children who are under 5 years of age, severe acute malnutrition is defined by a very low weight-for-height/weight-for-length or clinical signs of bilateral pitting oedema. A very low mid-upper arm circumference also indicates severe acute malnutrition in children who are 6–59 months of age. Severe acute malnutrition affects an estimated 19 million children under 5 years of age worldwide and is estimated to account for approximately 400,000 child deaths each year.
Children with severe acute malnutrition may have difficulty keeping themselves properly hydrated, however it can be difficult to assess the hydration status of severely malnourished children. As a result, fluid management is complex in children with severe acute malnutrition, particularly in those who have diarrhoea.
WHO recommendations
Children who are under 5 years of age with severe acute malnutrition who present with some dehydration or severe dehydration but who are not shocked should be rehydrated slowly, either orally or by nasogastric tube, with either
- ReSoMal, or
- half-strength standard WHO low-osmolarity oral rehydration solution with added potassium and glucose* at a rate of 5–10 mL/kg/h, for up to a maximum of 12 hours, unless the child has cholera or profuse watery diarrhoea. Children suspected of having cholera or have profuse watery diarrhoea should be given standard WHO low-osmolarity oral rehydration solution that is normally made, i.e. not further diluted.
* standard WHO low-osmolarity oral rehydration solution (75 mmol/L sodium) should not be used
This is a summary of one of several WHO recommendations on the management of SAM in infants and children. The full set of recommendations can be found in 'Full set of recommendations' and in the guidelines and guidance documents under ‘WHO documents’ below.
WHO documents
GRC-approved guidelines
-
Updates on the management of severe acute malnutrition in infants and children
Publication date: 2013 -
Pocket book of hospital care for children: second edition. Guidelines for the management of common illnesses with limited resources
Publication date: 2013
Other guidance documents
-
Diarrhoea treatment guidelines including new recommendations for the use of ORS and zinc supplementation for clinic-based healthcare workers
Publication date: 2005 -
The treatment of diarrhoea. A manual for physicians and other senior health workers
Publication date: 2005 -
Training course on the management of severe malnutrition
Publication date: 2002 (updated 2009) -
Management of severe malnutrition: a manual for physicians and other senior health workers
Publication date: 1999
Evidence
Systematic reviews used to develop the guidelines
-
Systematic review of the care of children with diarrhoea in the community-based management of severe acute malnutrition
pdf, 298kb
Manary M, Iannotti L, Trehan I, Weisz A.
Geneva: World Health Organization; 2012. -
The effectiveness of interventions to treat severe acute malnutrition in young children: a systematic review
Picot J, Hartwell D, Harris P, Mendes D, Clegg AJ, Takeda A.
Health Technology Assessment. 2012; 16(19):1-316.