e-Library of Evidence for Nutrition Actions (eLENA)

Donor human milk for low-birth-weight infants

Every year, more than 20 million infants are born weighing less than 2.5kg – over 96% of them in developing countries. These low-birth-weight (LBW) infants are at increased risk of early growth retardation, infectious disease, developmental delay and death during infancy and childhood.

Most LBW is a consequence of preterm birth, small size for gestational age, or both.

Interventions to improve the feeding of LBW infants are likely to improve the immediate and longer-term health and well-being of the individual infant and have a significant impact on neonatal and infant mortality levels in the population.

WHO recommends that LBW infants should be fed mother's own milk. When a mother's own breast milk is not available, the alternatives are either expressed breast milk from a donor mother or formula milk. Available evidence shows that compared with formula, donor human milk is associated with lower incidence of the severe gut disorder, necrotising enterocolitis, and other infections during the initial hospital stay after birth.

WHO recommendations

WHO recommends that LBW infants, including those with very low birth weight, who cannot be fed mother's own milk should be fed donor human milk.

This recommendation is relevant for settings where safe and affordable milk-banking facilities are available or can be set up.

This recommendation does not address sick LBW infants or infants with birth weight less than 1.0 kg.


This is one of several WHO recommendations on feeding of LBW infants. The full set of recommendations can be found in 'Full set of recommendations' and in the guideline, under ‘WHO documents’ below.

WHO documents


GRC-approved guidelines

Evidence


Systematic reviews used to develop the guidelines
Related Cochrane reviews
Other related systematic reviews
Clinical trials
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Last update:

19 December 2014 13:57 CET

Category 1 intervention

Guidelines have been recently approved by the WHO Guidelines Review Committee

Implementation

There is not yet any implementation information related to this intervention in GINA

Essential Nutrition Actions

This intervention is supported by Essential Nutrition Actions targeting the first 1000 days of life.