Long chain polyunsaturated fatty acid supplementation during pregnancy
n-3 long-chain polyunsaturated fatty acids may help regulate a number of biological processes including those that are important during pregnancy and delivery.
Marine foods are rich sources of n-3 long-chain polyunsaturated fatty acids and evidence from observational studies has suggested a potential association between consumption of marine foods during pregnancy and reduced risk of certain adverse health outcomes such as pre-eclampsia, preterm birth and low birth weight.
Current evidence suggests that supplementation with n-3 long-chain polyunsaturated fatty acids is associated with a reduced risk of preterm delivery and modest increase in birth weight, however further research is needed before specific recommendations can be made.
WHO recommendations
Further research is needed before specific recommendations can be made.
WHO documents
GRC-approved guidelines
Status: not currently available
Evidence
Related Cochrane reviews
-
Marine oil, and other prostaglandin precursor, supplementation for pregnancy uncomplicated by pre-eclampsia or intrauterine growth restriction
Makrides M, Duley L, Olsen SF.
Cochrane Database of Systematic Reviews. 2006; Issue 3. Art. No.: CD003402. - Summary of this review
Other related systematic reviews
-
Effect of n-3 Long-chain Polyunsaturated Fatty Acid Intake during Pregnancy on Maternal, Infant, and Child Health Outcomes: A Systematic Review
Imhoff-Kunsch B, Briggs V, Goldenberg T and Ramakrishnan U.
Paediatric and Perinatal Epidemiology. 2012; 26:91–107.