Vitamin B6 supplementation during pregnancy

Vitamin B6 is important for several metabolic processes, as well as development and functioning of the nervous system, primarily through the biosynthesis of neurotransmitters. Vitamin B6 is found in many foods including fish, meat, poultry, starchy vegetables and non-citrus fruits. Vitamin B6 deficiency alone is uncommon and occurs mostly in combination with deficiencies of other B vitamins.

It has been previously suggested that vitamin B6 might play a role in the prevention of pre-eclampsia and possibly preterm birth. Recent reviews of the literature indicate, however, that there is insufficient evidence on the benefits and harms, if any, of routine vitamin B6 (pyridoxine) supplementation during pregnancy, though it may provide some relief from pregnancy-related nausea.

Pregnant women should be encouraged to receive adequate nutrition, which is best achieved through consumption of a healthy balanced diet, and to refer to guidelines on healthy eating during pregnancy, where available.