While immunization is one of the most successful public health interventions, coverage  has held steady since 2024, but data highlight a troubling trajectory in progress toward key targets of the global Immunization Agenda 2030 (IA2030).  

During 2025, about 85% of infants worldwide (110 million) received 3 doses of diphtheria-tetanus-pertussis (DTP3) vaccine, protecting them against infectious diseases that can cause serious illness and disability or be fatal. However, these global figures hide significant disparity among countries of different income strata, with low-income countries lagging behind.

Measles, because of its high transmissibility, acts as an early warning system, quickly exposing immunity gaps in the population. Still, nearly 21 million children missed their routine first dose of measles, far from the 2019 level of 19 million.