Global situation and trends: In 2011, 8.7 million people fell ill with tuberculosis (TB), including 1.1 million cases among people with HIV. The estimated number of people falling ill with TB each year is declining slowly (at 2.2% per year between 2010 and 2011), which means that the world is on track to achieve the Millennium Development Goal to reverse the spread of TB by 2015. TB is second only to HIV/AIDS as the biggest killer worldwide due to a single infectious agent. In 2011, an estimated 1.4 million people died from TB, including 430 000 among people who were HIV-positive. These deaths included 0.5 million among women, making TB one of the top killers of women worldwide. The TB mortality rate fell 41% between 1990 and 2011 and the world is on track to achieve the global target of a 50% reduction by 2015.