Access to buprenorphine, methadone and oral morphine

Methadone and buprenorphine are both used in Opioid Substitution Therapy (OST), a proven medical intervention to treat dependence on opioid drugs, and morphine is the gold standard for combating pain, essential in order to provide adequate end-of-life care for people living with HIV/AIDS. However, all three medicines are controlled substances under the international drug control conventions and are not sufficiently available in many countries.

To improve access to those medicines, AMDS developed a database on sources and prices of methadone, buprenorphine, and oral morphine. This information is supplied by the pharmaceutical companies producing and distributing these medicines, and is made available for information only. The inclusion of any manufacturer in the database does not imply any endorsement of their product or company by the WHO.

UN guidance on procurement and registration procedures for controlled substances is also provided.