Antiretroviral drug resistance surveillance among drug-naive HIV-1-infected individuals in Gauteng Province, South Africa in 2002 and 2004
Antiviral Therapy Volume 13, 2008; Supplement 2: 101–107
The transmission of drug-resistant HIV-1 variants is being increasingly reported in countries where antiretroviral therapy has been in use for some time, in particular the United States and Europe but also in developing countries, such as Brazil. In South Africa, a country with an estimated 5.7 million HIV-infected individuals and almost 1000 AIDS deaths every day, a Comprehensive HIV and AIDS Care, Management and Treatment Plan was initiated in April 2004. The first line regimen in use is stavudine, lamivudine and efavirenz or nevirapine with Kaletra® being used among infants and children. At the end of September 2006, there were an estimated 235 000 people (10% of them children) receiving antiretroviral therapy through this programme; an additional 80 000 people were being treated in the private health care sector, where a variety of regimens are in use.
Co-produced with the International Medical Press.
© 2008 International Medical Press. Reproduced with permission.