Surveys to assess acquired HIV drug resistance
HIV drug resistance (HIVDR) prevention surveys support and builds upon early warning indicators (EWI) collection and includes viral load and HIVDR testing. The WHO generic protocol for monitoring HIVDR prevention during treatment in sentinel sites utilizes a standardized minimum-resource prospective survey methodology to assess the success of ART programmes in preventing HIVDR during the first year of treatment and identifies factors associated with the emergence of HIVDR which can be successfully addressed at the level of ART site and programmes.
Like EWIs, WHO HIVDR prevention surveys are designed to be integrated easily into a country’s ongoing, routine HIV-related evaluation activities. Performed regularly at representative sites, the data generated inform the evidence-base for national and global ART regimen selection and promotes efforts to minimize the emergence of HIVDR at a population level by effecting positive programmatic change if necessary.
HIV drug resistance status report 2009
Training of country coordinators, identification of suitable sentinel ART sites, and development and submission of country protocols for HIVDR monitoring surveys at sentinel ART sites has occurred in Burkina Faso, Ghana, Haiti, Kenya, Mozambique, Rwanda, Senegal, Ukraine, Vietnam and Zimbabwe. These countries are successfully adopting and piloting WHO HIVDR monitoring protocols in one to four sentinel ART sites in preparation for routine implementation of a rolling three year cycle of three to ten sites annually.