HIV/AIDS

2010 ART guidelines for adults and adolescents - evidence map

The 2010 revision of WHO Antiretroviral therapy for HIV infection in adults and adolescents, was based on a process of review and synthesis of new and emerging evidence. This process included consideration of systematic reviews, GRADE profiles, risk-benefit analyses, technical reports, as well as the findings from impact, feasibility and cost assessments, each contributing to the development of sound global recommendations.

These guidelines have been developed for a global audience and it is expected that to be effectively implemented, each country will adapt them to their local context.

To assist countries to adapt these new recommendations, all the evidence materials used in their creation are now available on the WHO website for use by programme managers, academic institutions and national ART advisory committees in updating guidelines for adults and adolescents according to their local circumstances.

Selected presentations


Evaluating evidence using GRADE methodology: selected articles

Summary of evidence, GRADE tables and risk-benefit analysis

When to start ART in HIV+ adults and adolescents

GRADE table

What to start in HIV+ adults and adolescents

GRADE tables

Risk-benefit analysis

ART in specific populations

TB/HIV co-infection

GRADE tables

HIV/HBV co-infection

GRADE tables

HIV+ pregnant women

When to switch ART in HIV+ adults and adolescents

GRADE tables

Second-line ART

GRADE tables

Third-line ART
HIV care interventions
Guiding principles
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