Immunization, Vaccines and Biologicals

WHO/EPI/GEN/93.14

Immunological Basis for Immunization - Module 4: Pertussis

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Module 4 of the series Immunological basis for immunization. This document may be used as a reference source, as part of training curricula or as a training aid. It contains clear descriptions of the following aspects of pertussis: antigens of pertussis organisms, antigens of whole cell pertussis vaccines, techniques for measuring antibody response, development antibodies due to natural stimulation, development of antibodies following vaccination with whole cell vaccine, the need to monitor pertussis vaccine efficacy, immunological aspects of acellular pertussis vaccine and implications for immunization programmes. (For a listing of the complete series, see Section 7.3.3.)

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