Immunization, Vaccines and Biologicals

Malaria Vaccine Advisory Committee (MALVAC)

Terms of reference and membership

Functions

The Malaria Vaccine Advisory Committee (MALVAC) provides advice to WHO on activities related to the development of malaria vaccines. The specific responsibilities of the Committee are:

  • To advise the Secretariat of the Initiative for Vaccine Research (IVR) on issues concerning malaria vaccine research and development, particularly those related to:
    • the facilitation of and coordination with the international malaria vaccine research and development (R&D) effort, with a special emphasis on public health needs of developing countries.
    • development of guidance on pre-clinical and clinical evaluation of malaria vaccines to support the eventual development of norms and standards around these vaccines.
  • To advise IVR on its workplan and to identify opportunities for new or neglected lines of research.
  • To make recommendations on scientists and institutions suitable to formulate and carry out specific research and development projects or other studies for IVR.
  • To assist in the establishment of subcommittees, expert working groups or study groups required to address issues relevant to specific aspects of malaria vaccine development.

The Committee

The WHO/IVR Malaria Vaccine Advisory Committee consists of no more than twelve members, appointed by the Director, IVB. Areas of expertise required for membership are in the following areas: public health and epidemiology, parasitology, malariology, immunology, biotechnology, vaccine trials, vaccinology and immunization.

Committee members are appointed following a transparent process, including an open call for nominations made on the IVR website. The call specifies the particular expertise sought as well as the Terms of Reference. Nominations are also solicited from partner agencies as well as from existing Committee members.

Members are selected in their personal capacities for their scientific and technical knowledge and experience, as well as for their commitment and willingness to volunteer the necessary time and effort. Members shall act as individual experts and not as representatives of their respective organizations or employers. Membership has a broad geographic representation and balance of gender from industrialized and developing countries.

Members are expected to attend WHO/IVR Malaria Vaccine Advisory Committee meetings and make available their advice in the interim, and may occasionally be asked to participate in other meetings as well as site-visits.

When traveling for WHO activities, members are reimbursed for travel costs and accommodation according to WHO standard procedures.

As a rule, members are appointed initially for two year, renewable for a maximum of two consecutive two-year terms (maximum six years). However, if a member misses two meetings, in the absence of sufficient justification (e.g. illness, inability to procure visa, cancellation of flights, etc.), his/her appointment will automatically end. Director, IVB may decide to appoint a new member in replacement of that member.

Depending on the expertise required for WHO activities, including the review of proposals submitted for support, the Advisory Committee may be supplemented by other experts, including those from other WHO advisory groups.

Members should be free of any significant conflict of interest. To this end, members are required to complete a declaration of interest form on an annual basis and their participation is subject to the evaluation of completed forms by the WHO Secretariat.

Members should be free of any significant conflict of interest. To this end, members are required to complete a declaration of interest form on an annual basis and their participation is subject to the evaluation of completed forms by the WHO Secretariat.

The Committee reports to WHO through the Director, IVB.

The Committee chair

The Chair is appointed by the Director, IVB, and has the following responsibilities:

  • to chair the meetings of the Advisory Committee;
  • to liaise with the IVR Secretariat between meetings and provide advice on a regular basis;
  • to review meeting reports and reports from any interim recommendations;
  • to represent the WHO/IVR Malaria Vaccine Advisory Committee at the request of the IVR Secretariat.

The duration of the appointment is three years with the possibility of one renewal; maximum of six years.

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