Immunization, Vaccines and Biologicals

Malaria vaccines

WHO activities

Tracking the global malaria vaccine portfolio

The WHO Initiative for Vaccine Research (IVR) tracks all clinical and advanced preclinical malaria vaccine projects activity in spreadsheets, updates of which are posted on the IVR web pages. These spreadsheets are known as the WHO Rainbow Tables, and are compiled with help from funders, sponsors and investigators around the world. A review of malaria vaccine clinical projects (see link to journal below) based on the Rainbow Table was published in the Malaria Journal in January 2012.

Guiding the policy process

The Joint Technical Expert Group on Malaria Vaccines (see link to JTEG site below) reviews data emerging from the ongoing Phase III trial of RTS,S/AS01 and jointly advises IVR and the WHO Global Malaria Programme on the results. Further information on the process for developing a WHO recommendation on the use of a malaria vaccine is also available on the IVR web site.

Providing a forum for malaria vaccine stakeholders

IVR acts as the Secretariat to the Malaria Vaccine Funders Group (see link below), which was established to facilitate exchange of information and opinions among internationally active funding bodies for malaria vaccine development. The group enables a better coordination of ongoing and planned vaccine research activities, and identifies areas of research that can be supported in a complementary manner.

In addition, IVR’s Malaria Vaccine Advisory Committee (MALVAC) is a scientific group of experts that meets regularly to address a specific theme; a recent meeting of the group in February 2012 discussed the accelerated development of second-generation malaria vaccines. Details of previous MALVAC meetings are available on the IVR web pages listed below.