Immunization, Vaccines and Biologicals


To win the fight against tuberculosis (TB), a comprehensive approach is needed that includes new and more effective vaccines as well as improved diagnostics and treatment. The Bacille Calmette-Guérin (BCG) vaccine developed in 1921 remains the only vaccine against TB. Unfortunately, it is only partially effective: it provides some protection against severe forms of pediatric TB, but is unreliable against adult pulmonary TB, which accounts for most of the disease burden worldwide. Although BCG is the most widely administered vaccine in the world, the number of TB cases have never been higher. There is therefore an urgent need for a new, safe and effective vaccine that prevents all forms of TB, including drug-resistant strains, in all age groups and in people with HIV.

WHO Position papers

Further information

Last updated: 4 February 2013