Immunization standards

Pandemrix vaccine and cases of narcolepsy

27 August 2010

WHO's attention has been drawn to reports of narcolepsy in Sweden and Finland allegedly related to vaccinations with Pandemrix, an adjuvanted 2009 influenza A (H1N1) vaccine produced by GSK. WHO notes that the European Medicines Agency (EMA) has launched a review to look carefully at all of the available data and determine whether there is sufficient evidence to establish a causal association between the vaccine and narcolepsy. WHO, through it's Global Advisory Committee on Vaccine Safety, is monitoring the situation closely.

Pending the outcome of the ongoing reviews, Pandemrix remains licensed for use by the EMA and prequalified by WHO. Given that the benefits of 2009 influenza A (H1N1) vaccines are established, WHO recommendations to immunize vulnerable populations remain unchanged.