Influenza vaccine (seasonal) - inactivated (10 dose vial)
Vaccine Trade Name: Vaxigrip
Vaccine Type: Seasonal Influenza, split virion, inactivated
Manufacturer: Sanofi Pasteur
Country of Manufacture: France
Date of prequalification: 30 June 2011
NRA of Record: ANSM
Pharmaceutical form: liquid
Presentation: 10 dose vial
Route of administration: intramuscular or deep subcutaneous
Vaccine Vial Monitor: Type 7
Shelf life: 12 months at 2 - 8°C
Secondary Packaging: carton of 10 vials
Cold Chain volume per dose (cm3): 2.38
Preservative: Thiomersal, 2 mcg/dose.
Handling of opened multi-dose vials: WHO recommends that opened vials of this vaccine should be discarded 6 hours after opening or at the end of the immunization session, whichever comes first.
Multi dose vaccines have considerable advantages in developing country immunization programmes, especially in campaign settings, as they are economical, occupy less space in the cold chain freeing free storage places for other important vaccines, and in many settings, preferable from the administration view point as well. These advantages, in the context of routine immunization, may become disadvantages due to the potential for high wastage rates. This vial presentation contains 10 doses which makes it prone to such wastage. Therefore the vaccine is more suitable for campaign settings, and users must weigh the significance of potentially high wastage in the context of routine vaccination programmes if they choose to use this vaccine brand.