Global Influenza Surveillance and Response System (GISRS)

Electron microscopic picture of an H5N1 virus.
Courtesy of WHO Collaborating Center for Studies on the Ecology of Influenza in Animals, Memphis, USA

Global influenza virological surveillance has been conducted through WHO's Global Influenza Surveillance and Response System (GISRS) for over half a century.

Formerly known as the Global Influenza Surveillance Network (GISN), the new name came into effect following the adoption of the Pandemic Influenza Preparedness (PIP) Framework in May 2011.

  • WHO GISRS monitors the evolution of influenza viruses and provides recommendations in areas including laboratory diagnostics, vaccines, antiviral susceptibility and risk assessment.
  • WHO GISRS also serves as a global alert mechanism for the emergence of influenza viruses with pandemic potential.

In focus

Established in 1952, the network currently comprises 143 institutions in 113 WHO Member States, which are recognized by WHO as National Influenza Centres, 6 WHO Collaborating Centres, 4 WHO Essential Regulatory Laboratories, 13 WHO H5 reference laboratories, and ad hoc groups established to address specific emerging issues.


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