WHO guidelines for investigation of human cases of avian influenza A(H5N1)

Epidemic and Pandemic Alert and Response (EPR)

Publication details

Publication date: 2007
Languages: English
WHO reference number: WHO/CDS/EPR/GIP/2006.4r1



This revised document replaces the version published in October 2006 and includes the following changes:

  • Revision of section on initiating an investigation
  • Revision of the sections on contact tracing, including the time frames for tracing
  • Monitoring of health-care workers
  • Revision and addition of technical references

This document provides a framework and approach for public health authorities and investigators at all levels to plan for and conduct investigations of human cases of A(H5N1) (or other novel influenza viruses of pandemic potential). The document focuses on the key steps that should be undertaken in an investigation.