Global action plan for influenza vaccines

Global Action Plan for Influenza Vaccines (GAP)

Global Action Plan for Influenza Vaccines (GAP) is a comprehensive strategy to reduce the present global shortage of influenza vaccines for seasonal epidemics and pandemic influenza in all countries of the world through three major approaches:
- Increase in seasonal vaccine use
- Increase in vaccine production capacity
- Research and development

GAP was launched in 2006 and further refined in 2011.

Objective 1: increase in seasonal vaccine use

The first GAP approach is to encourage countries to increase their seasonal vaccine use.
Increased use of seasonal influenza vaccine will reduce disease burden of seasonal influenza infections, contribute towards the preparedness of countries to respond to an eventual pandemic and motivate industry to develop greater capacity for manufacturing vaccines.

Objective 2: increase in vaccine production capacity

The second GAP approach concentrates on increasing production capacity for pandemic vaccines without expectation for a commensurate increase in the demand for seasonal vaccine.
Short term – produce enough vaccine to immunize two billion people; this vaccine should be available on the market six months after transfer of the vaccine prototype strain to industry.
Medium and long term – produce enough vaccine to immunize the world’s population (6.7 billion).

Objective 3: research and development

The third GAP approach encourages to use new technologies to develop more potent and effective influenza vaccines that are:
(a) capable of inducing protective responses after one dose, and/or
(b) induce broad-spectrum and long-lasting immunity against both seasonal and pandemic influenza strains.

About GAP:

What's new:

  • 24 May 2014

    GAP Progress Report: 2006-2013

    This is the first GAP global progress report that provides details on key highlights for the period from 2006, when GAP was launched, to September 2013. It is anticipated that regular updates will follow approximately every two years.

  • 9 October 2013

    APACI workshop: focusing on healthcare professionals

    The Asia-Pacific Alliance for the Control of Influenza (APACI) held the inaugural Asia-Pacific workshop with a particular focus on healthcare workers in Viet Nam. The Global Action Plan for Influenza Vaccines (GAP) was featured in two of the three sessions of the workshop.

  • 5-10 September 2013

    GAP at the Options Influenza Conference

    Recent progress, achievements and next steps under the GAP were presented in the Cape Town “Options for the Control of Influenza VIII Conference”, attended by more than 950 participants.

  • 11-13 June 2013

    Workshop on Enhancing Communication around Influenza Vaccination


OBJECTIVE 1________________

Universal paid leave increases influenza vaccinations among employees in the U.S.
1 May 2014/ Vaccine, Volume 32, Issue 21, pp 2441-2445

Vaccination contre la grippe saisonnière à Maurice
7 Avril 2014 /

When pregnant women receive the flu vaccine, their risk of developing influenza is halved
4 April 2014 / Medscape

OBJECTIVE 2_________________

A more efficient production process for influenza vaccines could help to cope with future pandemics
9 April 2014 / Medical Xpress

OBJECTIVE 3________________

HKU team hail H7N9 flu vaccine 'breakthrough'
3 April 2014 / South China Morning Post (China)


WHO says flu approaching interseasonal levels
7 April 2014 / CIDRAP
Not So Seasonal Influenza
7 April 2014 / The Nation (Pakistan)
Cambodia needs more actions to curb bird flu:PM
28 March 2014 / Shanghai Daily (China)


Contact us:

World Health Organization
Global Action Plan for Influenza Vaccines (GAP)
20, avenue Appia
1211 Geneva 27, Switzerland

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